[Topics on Child Development in Pediatrics]

Kyoko Hirasawa1

  • 1Department of Pediatrics, Tokyo Women's Medical University.

Summary

Very-low-birth-weight (VLBW) babies show higher rates of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). Long-term follow-up is crucial for these children to address developmental challenges.

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Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

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In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
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Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

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