Related Experiment Video
Updated: Feb 15, 2026

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure
Published on: July 30, 2009
[Topics on Child Development in Pediatrics]
1Department of Pediatrics, Tokyo Women's Medical University.
Insights
Very-low-birth-weight (VLBW) babies show higher rates of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). Long-term follow-up is crucial for these children to address developmental challenges.
Area of Science:
- Neonatal Medicine
- Developmental Pediatrics
- Neuroscience
Background:
- Neonatal medicine advances improve survival for very-low-birth-weight (VLBW) infants.
- Mild cognitive dysfunction is a growing concern in VLBW survivors.
Observation:
- Incidence of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) in VLBW infants at age 3 was 7.2%.
- This rate is significantly higher than the 2.8% incidence of ASD in the general population.
- By age 6, the incidence of these developmental disorders in VLBW children increased to 30%.
Findings:
- VLBW infants exhibit a substantially elevated risk for developmental disorders like ASD and ADHD.
- Developmental issues become more pronounced as VLBW children age, necessitating early and ongoing assessment.
Implications:
- Early identification and intervention are critical for VLBW children with developmental disorders.
- Comprehensive, long-term follow-up is essential for VLBW survivors through elementary school.
- Support strategies should focus on improving parent-child relationships and managing behavioral challenges.
Abstract:
Over the past few decades, advances in neonatal medicine have increased survival rates among very-low-birth-weight (VLBW) babies. Despite improvements in short-term outcomes, there is increasing concern about the probability of mild cognitive dysfunction in this population. Our analysis of VLBW babies born in our hospital revealed that the incidence of mild developmental disorders including autism spectrum disorder (ASD) and attention deficit hyperactive disorder (ADHD) at the age of 3 years is 7.2%, which is markedly higher than the 2.8% incidence of ASD in the general population. Because problems related to ASD or ADHD tend to become more prominent as children grow up, the ages at diagnosis of developmental disorders are generally 6 years or above. Thus, in our follow up study of VLBW babies at age 6, the incidence of these developmental disorders had risen to 30%. These patients are apparently obstinate and difficult to train, causing parental problems with child care. It is important to support these children and help them establish good relationships with their parents. Given these problems, it is necessary to follow up VLBW children in the longterm, at least until they are elementary school students.
More Related Videos
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Sustainable Development
Language Development
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...

