Related Experiment Video
Updated: Feb 15, 2026
11:19
Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
18.7K
Pediatric Chylopericardium: Treatment Conundrum.
Mitul Jasani1, Amar Shah1, Anirudh V Shah1
1Amardeep Multispeciality Children Hospital and Research Centre, Ahmedabad, Gujarat, India.
Journal of Indian Association of Pediatric Surgeons
|February 2, 2018
Summary
Primary chylopericardium, rare in children, involves chyle in the pericardial sac. Minimally invasive surgery offers a promising treatment approach for this challenging pediatric condition.
Area of Science:
- Pediatric Cardiology
- Thoracic Surgery
- Rare Diseases
Background:
- Primary chylopericardium is an uncommon condition in children, defined by lymphatic fluid accumulation within the pericardial sac.
- Current treatment options for pediatric chylopericardium lack a definitive curative approach, presenting a significant management challenge.
Observation:
- This study details the experience of managing pediatric primary chylopericardium.
- The focus is on the application of minimally invasive surgical techniques for treatment.
Findings:
- Minimally invasive surgery was employed to address primary chylopericardium in pediatric patients.
- The outcomes of this surgical approach are presented, highlighting its potential efficacy.
Implications:
- Minimally invasive surgery may represent a viable and effective treatment strategy for pediatric primary chylopericardium.
- Further research into surgical interventions could lead to improved management protocols for this rare condition.
Related Concept Videos
01:26Pharmacokinetics in Pediatric Patients: Drug Excretion
279
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
279
01:17Pharmacokinetics in Pediatric Patients: Drug Distribution
334
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
334
01:24Pharmacokinetics in Pediatric Patients: Drug Metabolism
251
In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
251
01:23Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
316
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
316
01:27Open Angle Glaucoma: Treatment
1.0K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.0K
02:56Treatment Resistant Cancers
3.8K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.8K