Paired Ear Creases of the Helix (PECH): A Possible Physical Sign

Pirunthan Pathmarajah1, Christopher Rowland Payne2

  • 1General Medicine, Whipps Cross Hospital.

Cureus
|February 2, 2018
PubMed

Insights

Frank's sign, or diagonal ear lobe creases, are linked to heart disease. This study introduces paired ear creases of the helix as a potential new cardiovascular risk indicator.

Area of Science:

  • Cardiology
  • Dermatology
  • Genetics

Background:

  • Diagonal ear lobe creases (Frank's sign) are associated with coronary artery disease.
  • The pathophysiology linking ear creases to cardiovascular disease remains unclear.

Observation:

  • A case report of a 68-year-old South Asian man with coronary artery disease and a diagonal ear lobe crease.
  • The patient also presented with previously unreported paired ear creases on the helix of the same ear.

Findings:

  • This is the first report of paired ear creases of the helix.
  • These helix creases may hold similar clinical significance for cardiovascular disease as diagonal ear lobe creases.

Implications:

  • Paired ear creases of the helix may represent a novel, observable sign for cardiovascular risk assessment.
  • Further research is needed to understand the pathophysiological mechanisms connecting ear creases (lobe and helix) to cardiovascular disease and metabolic syndrome.

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