Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Cells and Tissue01:30

Bone Cells and Tissue

8.6K
Bones contain a relatively small number of cells entrenched in a matrix of organic and inorganic components. Although bone cells compose only a small amount of the bone volume, they are crucial to its function. Four types of cells are found within the bone tissue— osteoblasts, osteocytes, osteogenic cells, and osteoclasts.
Osteoblasts and Osteocytes
The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the...
8.6K
Gravitational Potential Energy for Extended Objects01:07

Gravitational Potential Energy for Extended Objects

2.0K
Consider a system comprising several point masses. The coordinates of the center of mass for this system can be expressed as the summation of the product of each mass and its position vector divided by the total mass:
2.0K
¹H NMR of Labile Protons: Temporal Resolution01:10

¹H NMR of Labile Protons: Temporal Resolution

1.7K
Protons bonded to heteroatoms such as nitrogen and oxygen exhibit a range of chemical shift values. This is due to the varying degree of hydrogen bonding between the proton and the heteroatom in other molecules. The extent of hydrogen bonding affects the electron density around the proton, thereby giving different chemical shift values for the protons in the proton NMR spectrum.
The –OH proton in alcohols typically appears in the range of δ 2 to 5 ppm but can vary depending on the specific...
1.7K
Assessing Body Temperature - Temporal Artery01:19

Assessing Body Temperature - Temporal Artery

1.3K
Here is a stepwise guide to assessing the body temperature at the temporal artery using a temporal artery thermometer
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.  
Step 3: Assess the patient's...
1.3K
Bone Structure01:55

Bone Structure

52.0K
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
52.0K
Bone Remodeling01:40

Bone Remodeling

40.5K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
40.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Changes in audiovestibular handicap following treatment of vestibular schwannomas.

The Journal of laryngology and otology·2023
Same author

Facial Nerve Function Outcome and Risk Factors in Resection of Large Cystic Vestibular Schwannomas.

Journal of neurological surgery. Part B, Skull base·2022
Same author

Headache, Cerebrospinal Fluid Leaks, and Pseudomeningoceles after Resection of Vestibular Schwannomas: Efficacy of Venous Sinus Stenting Suggests Cranial Venous Outflow Compromise as a Unifying Pathophysiological Mechanism.

Journal of neurological surgery. Part B, Skull base·2019
Same author

Otolaryngology - Head and Neck Surgeon unemployment in Canada: a cross-sectional survey of graduating Otolaryngology - Head and Neck Surgery residents.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale·2015
Same author

Squamous cell carcinoma of the temporal bone: clinical outcomes from radical surgery and postoperative radiotherapy.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·2014
Same author

Magnetic resonance imaging after translabyrinthine complete excision of vestibular schwannomas.

Journal of neurological surgery. Part B, Skull base·2013

Related Experiment Video

Updated: Feb 15, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

860

Extended Temporal Bone Resection for Squamous Cell Carcinoma.

David A Moffat1, Philip Grey1, Robert H Ballagh1

  • 11 Department of Otoneurological and Skull Base Surgery, Addenbrooke's Hospital. Cambridge, United Kingdom.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|February 2, 2018
PubMed
Summary

Extended temporal bone resection offers encouraging salvage results for recurrent squamous cell carcinoma. This radical surgery, combined with radiotherapy, may improve 5-year survival rates compared to conventional treatments.

More Related Videos

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
10:43

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Published on: December 23, 2022

4.1K
Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression
07:53

Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression

Published on: March 17, 2020

7.7K

Related Experiment Videos

Last Updated: Feb 15, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

860
Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
10:43

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Published on: December 23, 2022

4.1K
Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression
07:53

Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression

Published on: March 17, 2020

7.7K

Area of Science:

  • Otolaryngology
  • Surgical Oncology
  • Head and Neck Surgery

Background:

  • Squamous cell carcinoma of the temporal bone often requires salvage treatment for recurrence.
  • Conventional treatments like radiotherapy or partial temporal bone resection yield low 5-year survival rates.
  • Advanced tumors and poorly differentiated histology are associated with a poor prognosis.

Purpose of the Study:

  • To evaluate the surgical outcomes of extended temporal bone resection as a salvage procedure for recurrent squamous cell carcinoma.
  • To assess the efficacy of this radical approach in improving patient survival.

Main Methods:

  • Retrospective analysis of 15 patients undergoing extended temporal bone resection.
  • Procedures included supraomohyoid block dissection, dural grafting, and free microvascular flap reconstruction.
  • Salvage surgery was performed in a radical mastoid cavity for recurrent disease.

Main Results:

  • A 47% 5-year survival rate was achieved with radical surgery.
  • Temporal lobe involvement requiring partial excision occurred in 29% of survivors.
  • Histologic evidence of lymph node metastasis was found in 13% of cases.
  • All deaths occurred within the first postoperative year.
  • Survivors predominantly had well or moderately differentiated tumors.

Conclusions:

  • Extended temporal bone resection demonstrates encouraging results as a salvage therapy for recurrent squamous cell carcinoma.
  • Radical surgery combined with radiotherapy may offer superior 5-year survival compared to conventional partial resections and radiotherapy.
  • Future treatment strategies should consider aggressive surgical intervention for advanced or recurrent temporal bone squamous cell carcinoma.