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Updated: Feb 15, 2026
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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
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Parenteral antithrombotic therapy during primary percutaneous coronary intervention
Federico Fortuni1,2, Marco Ferlini3, Sergio Leonardi3
1University of Pavia, Pavia, Italy - fortuni@alice.it.
Minerva Cardioangiologica
|February 3, 2018
Summary
Acute myocardial infarction (AMI) is a global health issue. This overview focuses on parenteral antithrombotic therapies for ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (pPCI).
Area of Science:
- Cardiology
- Pharmacology
Background:
- Acute myocardial infarction (AMI) is a leading cause of global morbidity and mortality.
- ST-segment elevation myocardial infarction (STEMI) constitutes a significant portion of AMI cases.
- Arterial thrombosis, driven by atherosclerotic plaque rupture, is the primary cause of STEMI.
Purpose of the Study:
- To provide an overview of parenteral antithrombotic therapies.
- To discuss treatments for patients with STEMI undergoing primary percutaneous coronary intervention (pPCI).
Main Methods:
- Review of currently available parenteral antithrombotic agents.
- Focus on their use in the context of pPCI for STEMI.
Main Results:
- Platelets and coagulation factors are key players in STEMI pathogenesis.
- Early reperfusion is the critical treatment goal for STEMI.
- pPCI combined with antithrombotic therapy is the standard of care.
Conclusions:
- Parenteral antithrombotic therapies are essential in managing STEMI patients undergoing pPCI.
- Understanding these therapies is crucial for effective STEMI treatment.
- Optimizing antithrombotic strategies improves patient outcomes.
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