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Updated: Feb 15, 2026

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems
Published on: July 4, 2011
A Fluorescent Ditopic Rotaxane Ion-Pair Host
Mathieu Denis1, Lei Qin2, Peter Turner2
1Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK.
Abstract:
We report a rotaxane based on a simple urea motif that binds Cl- selectively as a separated ion pair with H+ and reports the anion binding event through a fluorescence switch-on response. The host selectively binds Cl- over more basic anions, which deprotonate the framework, and less basic anions, which bind more weakly. The mechanical bond also imparts size selectivity to the ditopic host.
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