[Experience with Using the EnCor ENSPIRE®System in Mammary Tissue Biopsy]

Area of Science:

• Oncology
• Radiology
• Pathology

Background:

• Accurate initial diagnosis of breast tumors is crucial for effective treatment planning.
• Minimally invasive biopsy techniques aim to improve diagnostic yield and patient comfort.
• Vacuum-assisted biopsy (VAB) offers potential advantages over traditional methods.

Purpose of the Study:

• To evaluate the diagnostic usefulness and accuracy of the EnCor ENSPIRE® system for vacuum-assisted biopsy (VAB) of breast tumors.
• To assess the VAB's performance in cases where core needle biopsy was inconclusive.

Main Methods:

• Retrospective analysis of 24 breast tumor cases undergoing VAB with the EnCor ENSPIRE® system.
• Review of histopathological diagnoses from VAB and subsequent tumor resections.
• Comparison of VAB results with core needle biopsy findings in select cases.

Main Results:

• 50.0% of VAB cases (12/24) were diagnosed as malignant, including invasive ductal carcinoma (IDC) and ductal carcinoma in situ (DCIS).
• VAB provided definitive diagnoses for various benign and malignant lesions, including intraductal papilloma (IDP) and atypical ductal hyperplasia (ADH).
• In 15 cases where core needle biopsy was inconclusive, VAB successfully diagnosed malignancies (IDC, DCIS) and benign conditions.

Conclusions:

• The EnCor ENSPIRE® system is a convenient and accurate tool for initial breast tumor biopsy.
• VAB using this system demonstrates high diagnostic utility for both malignant and benign breast lesions.
• No complications were reported, highlighting the safety of the procedure.