Related Experiment Video
Updated: Feb 15, 2026

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
Colonization of preservation solution in kidney transplantation: Clinical impact and risk of secondary acute graft
F Encatassamy1, A-S Valentin2, J Capsec3
1Department of Urology, University Hospital of Tours, Loire Valley, 2, boulevard Tonnellé, 37044 Tours, France.
Introduction:
Bacterial colonization of preservative solutions (PS) remains poorly described in renal transplantation. We investigated the bacterial colonization of the PS and its influence on graft pyelonephritis within one year from the renal transplantation.
Patients And Methods:
We cultured 2 samples of PS from 424 patients who underwent a renal transplantation. The follow-up period was one year. An acute graft pyelonephritis was defined as a positive bacteriological urine analysis, with temperature higher than 38.5°C or graft pain.
Results:
In total, 424 samples of PS were tested and 195 were positive for colonization (46%). Forty-five patients developed an acute graft pyelonephritis during the follow-up period (10.6%), of which, 21 (46.7%) showed a colonization of their PS. Twenty-four had no colonization (53.3%). This difference was not significant (P=0.697).
Discussion:
Our data suggest that the bacterial colonization of PS samples does not seem to increase the risk of acute graft pyelonephritis in renal transplant recipients.
Level Of Evidence:
-3.
Related Concept Videos
Acute Pyelonephritis I: Introduction
Acute Kidney Injury III: Clinical Manifestations
Acute Pyelonephritis II: Diagnostic Studies and Management
Kidney Transplant I: Introduction
Acute Kidney Injury I: Introduction
Acute Kidney Injury II: Pathophysiology

