Related Experiment Video

Updated: May 5, 2026

Generation of Induced Regulatory T Cells from Primary Human Naïve and Memory T Cells
14:23

Generation of Induced Regulatory T Cells from Primary Human Naïve and Memory T Cells

Published on: April 16, 2012

22.8K

Human regulatory T-cell subsets

M Young, R S Geha

    Annual Review of Medicine
    |January 1, 1986
    PubMed

    The immune response is under the regulation of T-cell populations that are characterized by defined cell surface markers. The differentiation and functional heterogeneity of these T-cell subsets are discussed in normal and disease states.

    More Related Videos

    Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets07:12

    Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

    Published on: April 16, 2015

    52.8K
    Generation of Human Chimeric Antigen Receptor Regulatory T Cells10:29

    Generation of Human Chimeric Antigen Receptor Regulatory T Cells

    Published on: January 3, 2025

    2.4K

    Related Concept Videos

    T Cell Activation and Clonal Selection01:22

    T Cell Activation and Clonal Selection

    T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
    Naive T cells that have not yet encountered an antigen express two primary CD...
    13.7K
    T Cell Types and Functions01:24

    T Cell Types and Functions

    When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
    Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
    3.2K