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A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
Hemodialysis access thrombosis
Keith Bertram Quencer1, Rahmi Oklu2
1Division of Interventional Radiology, Department of Radiology, University of Utah, Salt Lake City, UT, USA.
Insights
Arteriovenous (AV) access thrombosis is a major complication for hemodialysis patients, often leading to lost access. Percutaneous declotting methods offer alternatives to surgery for managing AV access thrombosis.
Area of Science:
- Nephrology
- Vascular Surgery
- Interventional Radiology
Background:
- Over 400,000 patients in the US rely on hemodialysis.
- Arteriovenous (AV) access thrombosis is a common and serious complication.
- Thrombosis leads to missed dialysis, hospitalizations, and permanent access loss.
Purpose of the Study:
- To review the current percutaneous treatment options for AV access thrombosis.
- To highlight the advantages of percutaneous methods over surgical thrombectomy.
Main Methods:
- Review of existing literature on percutaneous declotting techniques.
- Comparison of different percutaneous approaches: lyse-and-wait, thromboaspiration, pulse spray, and mechanical thrombectomy devices.
Main Results:
- Percutaneous declotting is the preferred method for AV access thrombosis.
- Multiple percutaneous techniques are available, each with potential benefits.
- These methods aim to restore AV access patency and prevent permanent loss.
Conclusions:
- Percutaneous declotting offers effective management for AV access thrombosis in hemodialysis patients.
- A range of percutaneous techniques allows for tailored treatment strategies.
- Minimizing complications like missed dialysis and access loss is crucial for patient care.
Abstract:
For the over 400,000 patients in the United States dependent on hemodialysis, arteriovenous (AV) access thrombosis may lead to missed dialysis sessions, inpatient admissions and the need for placement of temporary dialysis catheters. It is also the leading cause of permanent access loss. Percutaneous declotting is generally preferred over surgical thrombectomy. Various percutaneous approaches can be employed including the lyse-and-wait technique, thromboaspiration, pulse spray aided pharmacomechanical thrombolysis, and use of mechanical thrombectomy device.
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