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Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination
Published on: February 9, 2021
Disseminated actinomycetoma due to Nocardia wallacei
Oliverio Welsh1, Mario C Salinas-Carmona1, Barbara A Brown-Elliott2
1Universidad Autonoma de Nuevo Leon, Facultad de Medicina y Hospital Universitario Dr. Jose Gonzalez, Monterrey, Mexico.
Background:
Actinomycetoma caused by Nocardia usually responds well to antibiotics. Emerging species of Nocardia, such as N. wallacei, can be a therapeutic challenge.
Aims:
Confirm the therapeutic effectivity of linezolid in multidrug resistant Nocardia Wallacei actinomycetoma.
Materials And Methods:
We evaluated the medical management of an 18-year-old man with multidrug resistant actinomycetoma of the left leg caused by N. transvalensis complex treated 17 years ago with linezolid 1200 mg a day. This bacteria was recently reclassified as Nocardia Wallacei by specific molecular biology technique.
Results:
The infection was cured after 3 months of treatment; the patient remained asymptomatic for the past 17 years. No adverse effects were found.
Discussion:
Frequently, strains of N. transvalensis complex have aminoglycoside resistance; in this case, we highlight the effectiveness of linezolid for the successful medical management of multidrug resistant actinomycetoma.
Conclusion:
Linezolid can be an alternative for the treatment of multidrug resistant Nocardia Wallacei.
