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Development of apical hypertrophic cardiomyopathy
Danish Medical Bulletin
|April 1, 1986
Summary
This case study shows hypertrophic cardiomyopathy (HCM) can progress to apical HCM, forming an "ace of spades" shape. This progression did not affect the patient's symptoms or hemodynamics over nine years.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Clinical Medicine
Background:
- Hypertrophic cardiomyopathy (HCM) is a complex cardiac condition.
- Apical HCM is a distinct morphological variant.
- The progression of HCM requires further investigation.
Observation:
- A 40-year-old male with mild, diffuse HCM developed marked left ventricular apical hypertrophy over nine years.
- The apical HCM exhibited a characteristic
Findings:
- The left ventriculogram revealed a distinct "ace of spades" diastolic configuration.
- Electrocardiogram (ECG) showed persistent inverted T-waves.
- Increased precordial QRS amplitude and corrected QT-interval were observed during follow-up.
Implications:
- This case supports the hypothesis of evolving or "abortive" forms of apical HCM.
- Morphological progression of apical HCM can occur without clinical or hemodynamic changes.
- Understanding HCM progression is crucial for patient management and prognosis.