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Updated: Feb 15, 2026

Multidimensional Coculture System to Model Lung Squamous Carcinoma Progression
Published on: March 17, 2020
A Case of Small Cell Lung Carcinoma in a 15-Year-Old Boy and Literature Review
Mustafa Barbour1, Kenneth E Bujold2, Brian Joel Tjarks3
1Department of Pediatric Hematology-Oncology, University of Louisville School of Medicine, Louisville, KY.
Abstract:
Small cell lung carcinoma (SCLC), also known as high-grade neuroendocrine tumor of the lung, is exceedingly rare in the pediatric population. SCLC is usually fast growing and often has metastasized at diagnosis. It frequently responds well to therapy initially, however, has a high relapse and mortality rate. There are limited published data on SCLC in children and no existing pediatric treatment protocols. In this report, we present a case of extensive stage SCLC in a 15-year-old boy who responded to single-agent gemcitabine therapy and review similar cases reported in the medical literature.
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