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Updated: Feb 14, 2026

Electrospinning Growth Factor Releasing Microspheres into Fibrous Scaffolds
Published on: August 16, 2014
Development and characterization of ethylcellulose based microsphere for sustained release of nifedipine
Patitapabana Parida1, Subash Chandra Mishra2, Subhashree Sahoo3
1Department of Biotechnology and Medical Engineering, NIT Rourkela, Odisha 769008, India.
Abstract:
This article introduced the work of ethylcellulose based polymeric microsphere loaded with nifedipine for reduction in frequency of administration with low solubility in aqueous medium and high rate of absorption in the stomach. The non-aqueous polymeric suspension was put dropwise into an aqueous medium containing polyvinyl alcohol as a surfactant for the synthesis of microsphere by solvent evaporation. The microspheres were characterized by different techniques, namely, XRD, SEM, and NMR. The formation of microspheres was confirmed by SEM. XRD analysis revealed the semi-crystallinity nature of microspheres. The NMR study indicated the presence of hetero-aromatic nucleus in the microsphere.
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