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Updated: Feb 14, 2026

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Published on: February 14, 2025
Right Sided Aortic Arch Resembling Asthma.
Sami İlhan1, Ahmet Bolukçu2, Rafet Günay2
1Clinic of Chest Diseases, Dr. Siyami Ersek Chest and Cardiovascular Surgery Training and Research Hospital, İstanbul, Turkey.
A rare aortic arch anomaly caused a patient's persistent shortness of breath, unresponsive to asthma treatment. Correct diagnosis of this right sided aortic arch resolved symptoms and unnecessary medical interventions.
Area of Science:
- Cardiology
- Pulmonology
- Medical Imaging
Background:
- Dyspnoea is a common asthma symptom, but persistent cases despite optimal treatment suggest infrequent causes.
- A 38-year-old patient experienced five years of refractory dyspnoea, unresponsive to standard asthma medications like salbutamol and budesonide/formoterol inhalations.
Purpose of the Study:
- To identify the underlying cause of persistent dyspnoea in a patient with a history of asthma.
- To highlight the diagnostic challenges and implications of delayed diagnosis for rare vascular anomalies causing respiratory symptoms.
Main Methods:
- Clinical case presentation of a patient with prolonged dyspnoea.
- Diagnostic workup including chest radiography and spirometry.
- Advanced imaging with contrast-enhanced computed tomography (CT) or angiography for definitive diagnosis.
Main Results:
- A right sided aortic arch was diagnosed as the cause of the patient's persistent dyspnoea.
- This rare anomaly can compress the trachea and oesophagus, mimicking respiratory conditions.
- Initial investigations like chest X-ray and spirometry showed some signs, but CT/angiography confirmed the diagnosis.
Conclusions:
- Persistent dyspnoea unresponsive to asthma therapy may indicate rare underlying conditions like a right sided aortic arch.
- Timely diagnosis through appropriate imaging is crucial to avoid prolonged ineffective treatments and unnecessary investigations.
- Identifying and treating the vascular anomaly led to symptom improvement and cessation of inappropriate asthma management.
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