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Juvenile Angiofibroma: Current Management Strategies.

Ahmad Safadi1, Alberto Schreiber2, Dan M Fliss1

  • 1Department of Otorhinolaryngology - Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Journal of Neurological Surgery. Part B, Skull Base
|February 7, 2018
PubMed
Summary

Juvenile angiofibroma (JA) is a benign, vascular tumor diagnosed via clinical and imaging findings. Endoscopic endonasal surgery is the preferred treatment for most JAs, even advanced cases, in experienced centers.

Keywords:
endoscopic surgeryjuvenile angiofibromasurgical treatment of juvenile angiofibroma

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Area of Science:

  • Otolaryngology
  • Head and Neck Surgery
  • Oncology

Background:

  • Juvenile angiofibroma (JA) is a rare, benign, and highly vascular tumor.
  • JA typically affects adolescents and young adults, originating in the nasal cavity.
  • It characteristically spreads to the pterygopalatine fossa and pterygoid base.

Purpose of the Study:

  • To review the diagnosis and treatment of juvenile angiofibroma.
  • To highlight the role of endoscopic endonasal surgery in managing JA.
  • To emphasize the importance of experienced surgical centers for optimal outcomes.

Main Methods:

  • Diagnosis relies on clinical presentation and characteristic imaging features.
  • Surgical resection is the primary treatment modality for JA.
  • Radiotherapy is reserved for rare recurrent cases.

Main Results:

  • Endoscopic endonasal surgery is the current treatment of choice for small to intermediate JAs.
  • This minimally invasive approach is also feasible for advanced JA.
  • Successful outcomes depend on the surgeon's expertise and center experience.

Conclusions:

  • Juvenile angiofibroma requires accurate diagnosis based on clinical and imaging data.
  • Endoscopic endonasal surgery offers a safe and effective treatment for JA.
  • Management of JA should be centralized in experienced high-volume centers to ensure optimal patient care and outcomes.