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Updated: Feb 14, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Nasoseptal Flap for Skull Base Reconstruction in Children
Oded Ben-Ari1, Anat Wengier1, Barak Ringel1
1Department of Otolaryngology Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Vascularized nasoseptal flaps (NSF) are effective and safe for reconstructing anterior skull base defects in children, showing a low complication rate and no negative impact on craniofacial growth.
Area of Science:
- Neurosurgery
- Otolaryngology
- Pediatric Surgery
Background:
- Endoscopic endonasal approach (EEA) is increasingly used for anterior skull base (ASB) lesions.
- Vascularized nasoseptal flaps (NSF) are crucial for ASB defect reconstruction, reducing cerebrospinal fluid (CSF) leaks.
Purpose of the Study:
- To evaluate the efficacy and safety of NSF in pediatric patients undergoing ASB defect repair.
Main Methods:
- Retrospective analysis of 12 pediatric patients (<18 years) undergoing endoscopic endonasal NSF repair of ASB defects (2011-2016).
- Inclusion of patients with benign/malignant neoplasms and prior ASB surgery.
Main Results:
- Successful reconstruction in 12 children with a male-to-female ratio of 1:1 and average age of 12.3 years.
- Average hospitalization: 8.3 days; maximum follow-up: 24 months.
- Low complication rate: 2 cases of crusting/synechia, 1 CSF leak with meningitis; craniofacial growth unimpaired.
Conclusions:
- Endoscopic endonasal NSF is an effective and safe technique for ASB defect reconstruction in pediatric patients.
- High success rate and low complication profile observed.
- No adverse effects on craniofacial growth noted in this pediatric series.
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