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Updated: Feb 14, 2026

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
A copper-catalyzed carbonylative four-component reaction of ethene and aliphatic olefins
Yahui Li1, Fengxiang Zhu, Zechao Wang
1Leibniz-Institut für Katalyse e. V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock, Germany. Xiao-Feng.Wu@catalysis.de.
Abstract:
To have a balance between reactivity and selectivity has been a long-standing challenge in multicomponent reactions. In this communication, a carbonylative four-component reaction has been developed. With copper as the catalyst, using ethene including other aliphatic alkenes, alcohols and acetonitrile as the substrates under CO pressure, various desired products were produced in moderate to good yields. The obtained products can be applied in the synthesis of δ-valerolactams. Good functional group tolerance and reaction efficiency can be observed here.
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