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Updated: Feb 14, 2026

Novel Approach for Simultaneous Recording of Renal Sympathetic Nerve Activity and Blood Pressure with Intravenous Infusion in Conscious, Unrestrained Mice.
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Intravenous fluids: effects on renal outcomes.

D J McLean1, A D Shaw2

  • 1Department of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, Rochester, NY, USA.

British Journal of Anaesthesia
|February 7, 2018
PubMed
Summary
This summary is machine-generated.

Intravenous fluid therapy, a common inpatient treatment, significantly impacts kidney function. Careful administration of intravenous fluids is crucial for patient recovery and renal outcomes.

Keywords:
colloidscritical carecrystalloidsgoal-directed fluid therapyperi-operativerenal insufficiencyresuscitation

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Area of Science:

  • Nephrology
  • Critical Care Medicine
  • Hospital Pharmacy

Background:

  • Intravenous fluid therapy is a ubiquitous inpatient medication.
  • Intravenous fluids possess pharmacological properties, including indications, dosages, and potential adverse effects.
  • The type and volume of administered fluids critically influence patient recovery trajectories.

Purpose of the Study:

  • To review the impact of intravenous fluid administration on kidney function.
  • To summarize renal outcome measures relevant to clinicians and patients.
  • To highlight the ongoing evolution of fluid therapy practices.

Main Methods:

  • This study is a narrative review.
  • It synthesizes existing literature on intravenous fluid therapy and renal outcomes.
  • It discusses the implications for clinical practice.

Main Results:

  • Intravenous fluid administration directly affects kidney function.
  • Both the type and amount of fluid are critical determinants of renal outcomes.
  • Current evidence suggests a significant impact on recovery, necessitating careful consideration.

Conclusions:

  • Intravenous fluid therapy requires judicious administration to optimize renal outcomes.
  • Ongoing clinical trials are poised to refine current fluid therapy guidelines.
  • Understanding the renal effects of intravenous fluids is essential for patient care.