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Related Experiment Video

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Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
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Functional abdominal pain disorders in children.

Shaman Rajindrajith1, Judith Zeevenhooven2, Niranga Manjuri Devanarayana3

  • 1a Department of Paediatrics, Faculty of Medicine , University of Kelaniya , Ragama , Sri Lanka.

Expert Review of Gastroenterology & Hepatology
|February 7, 2018
PubMed
Summary

Functional abdominal pain disorders (FAPDs) affect 13.5% of children globally. While non-pharmacological therapies show promise, accessible and effective treatments for pediatric chronic abdominal pain are needed.

Keywords:
Abdominal painRome criteriaantidepressantsbehavioral therapychild maltreatmentfunctional dyspepsiahypnotherapyirritable bowel syndromeprokinetics

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Area of Science:

  • Pediatric Gastroenterology
  • Functional Abdominal Pain Disorders

Background:

  • Chronic abdominal pain is prevalent in children, often meeting Rome IV criteria for functional abdominal pain disorders (FAPDs).
  • These conditions can have significant negative impacts on a child's well-being.

Purpose of the Study:

  • To review current knowledge on the epidemiology, pathophysiology, risk factors, clinical evaluation, and management of FAPDs in children.
  • To highlight the efficacy of non-pharmacological interventions and the need for improved therapeutic approaches.

Main Methods:

  • Comprehensive review of existing literature on pediatric FAPDs.
  • Analysis of epidemiological data, pathophysiological mechanisms, and treatment outcomes.

Main Results:

  • FAPDs have a pooled global prevalence of 13.5%, influenced by factors like stress, maltreatment, visceral hypersensitivity, altered gut motility, and microbiota changes.
  • Pharmacological treatments offer limited symptom relief; however, hypnotherapy and cognitive behavioral therapy demonstrate short- and long-term efficacy.
  • Current non-pharmacological interventions are resource-intensive and not widely accessible.

Conclusions:

  • Developing more pragmatic and effective treatments for pediatric FAPDs is crucial.
  • Collaboration between clinicians and researchers is essential to enhance care for children suffering from chronic abdominal pain.