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Managing Dyslipidemia in Type 2 Diabetes

Adam J Nelson1, Simon K Rochelau1, Stephen J Nicholls1

  • 1South Australian Health and Medical Research Institute, PO Box 11060, Adelaide, SA 5001, Australia.

Endocrinology and Metabolism Clinics of North America
|February 7, 2018
PubMed

Insights

Individuals with diabetes face a higher risk of cardiovascular disease and atherosclerotic events. Effective management of diabetic dyslipidemia is crucial for mitigating these risks.

Area of Science:

  • Endocrinology
  • Cardiology
  • Metabolic Disorders

Background:

  • Cardiovascular disease (CVD) is a leading cause of death in diabetic patients.
  • Diabetics have a twofold higher risk of atherosclerotic events despite risk reduction efforts.
  • Insulin resistance in diabetes alters lipid profiles, complicating treatment.

Purpose of the Study:

  • To review the background of diabetic dyslipidemia.
  • To summarize current management strategies for diabetic dyslipidemia.

Main Methods:

  • Literature review of studies on diabetes, dyslipidemia, and cardiovascular disease.
  • Analysis of lipid profile changes associated with diabetes and insulin resistance.
  • Overview of established and emerging treatment options.

Main Results:

  • Diabetic dyslipidemia is characterized by specific lipid profile abnormalities.
  • Aggressive management of traditional risk factors is essential.
  • Current treatments aim to normalize lipid levels and reduce cardiovascular risk.

Conclusions:

  • Diabetic dyslipidemia significantly increases cardiovascular morbidity and mortality.
  • Comprehensive management of lipid disorders is a cornerstone of cardiovascular risk reduction in diabetes.
  • Further research into optimal therapeutic approaches is warranted.

Keywords:
DiabetesDyslipidemiaLDLStatinTriglycerides

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