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Occupational rhinitis and occupational asthma: Association or progression?
Rahmat A Balogun1, Andrea Siracusa2, Dennis Shusterman1
1Division of Occupational and Environmental Medicine, University of California, San Francisco, California.
American Journal of Industrial Medicine
|February 8, 2018
Summary
Occupational rhinitis may precede occupational asthma, especially with high-molecular-weight agents. More research is needed due to limited data and cross-tabulation in studies on these occupational respiratory diseases.
Area of Science:
- Occupational Medicine
- Epidemiology
- Respiratory Health
Background:
- Occupational asthma is a leading reported occupational respiratory disease.
- It is frequently diagnosed alongside occupational rhinitis.
- This review focuses on the progression from occupational rhinitis to occupational asthma.
Purpose of the Study:
- To systematically review epidemiologic literature on the link between occupational rhinitis and asthma.
- To investigate the progression from occupational rhinitis to occupational asthma.
Main Methods:
- Systematic review of English-language literature.
- Searches conducted on PubMed and Embase databases.
- Studies comparing incidence or prevalence in occupationally exposed individuals were identified.
Main Results:
- 109 unique citations were identified.
- 15 studies provided data on the occupational rhinitis-asthma relationship.
- Nine of these 15 studies showed a statistically significant association between occupational rhinitis and asthma in workers.
Conclusions:
- Limited evidence suggests occupational rhinitis can precede occupational asthma, particularly with high-molecular-weight agents.
- Many studies lacked cross-tabulation, hindering evaluation of the relationship.
- Further research is needed to clarify the progression.
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