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Generation of Fluorescent Protein Fusions in Candida Species
Published on: March 4, 2017
Abstract:
Fungal infections of the skin represent a relatively common problem in pediatric dermatology. Although fungal infections of the feet, nails, and groin are uncommon in the pediatric age group, fungal infections of the scalp are very common and must be diagnosed early because they may lead to permanent hair loss if left untreated. Perhaps the most significant change in fungal infections in children has occurred in tinea capitis, including the causative agent and the type of infection this organism may produce; these factors are focused upon in this article. Also discussed are infections caused by the yeast organisms Candida albicans and Pityrosporum orbiculare, as well as the deep mycoses, specifically chromoblastomycosis and cutaneous aspergillosis.
Insights
Pediatric fungal skin infections, especially tinea capitis (scalp ringworm), require early diagnosis to prevent permanent hair loss. This article reviews common pediatric fungal infections, focusing on scalp infections and causative agents.
Area of Science:
- Pediatric Dermatology
- Mycology
- Infectious Diseases
Background:
- Fungal skin infections are common in children.
- Scalp infections (tinea capitis) are particularly prevalent and can cause irreversible hair loss if untreated.
- While foot, nail, and groin infections are rare in children, scalp infections warrant prompt diagnosis and management.
Purpose of the Study:
- To review common fungal skin infections in pediatric patients.
- To highlight the changing landscape of tinea capitis, including causative agents and infection types.
- To discuss other significant fungal pathogens like Candida albicans, Pityrosporum orbiculare, and agents of deep mycoses.
Main Methods:
- Literature review focusing on pediatric fungal dermatoses.
- Analysis of current trends in causative agents for tinea capitis.
- Discussion of clinical presentations and diagnostic considerations for various fungal infections.
Main Results:
- Tinea capitis is a significant concern in pediatric dermatology due to its prevalence and potential for permanent alopecia.
- Changes in the predominant causative agents of tinea capitis have been observed.
- Other fungal pathogens, including yeasts and agents of deep mycoses, are also relevant in pediatric cases.
Conclusions:
- Early diagnosis and appropriate treatment of pediatric fungal infections, particularly tinea capitis, are crucial to prevent long-term sequelae such as hair loss.
- Understanding the evolving epidemiology of fungal pathogens in children is essential for effective management.
- A comprehensive approach is needed to address various fungal infections encountered in pediatric dermatology.
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