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Updated: Feb 14, 2026

Gold Nanoparticle Synthesis
Published on: July 10, 2021
Reversible Clustering of Gold Nanoparticles under Confinement
Ana Sánchez-Iglesias1, Nathalie Claes2, Diego M Solís3
1CIC biomaGUNE, CIBER-BBN, Paseo de Miramón 182, 2014, Donostia-San Sebastián, Spain.
Abstract:
A limiting factor of solvent-induced nanoparticle self-assembly is the need for constant sample dilution in assembly/disassembly cycles. Changes in the nanoparticle concentration alter the kinetics of the subsequent assembly process, limiting optical signal recovery. Herein, we show that upon confining hydrophobic nanoparticles in permeable silica nanocapsules, the number of nanoparticles participating in cyclic aggregation remains constant despite bulk changes in solution, leading to highly reproducible plasmon band shifts at different solvent compositions.
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