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Related Concept Videos

Types of Fever01:25

Types of Fever

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Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
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Patterns of Fever01:26

Patterns of Fever

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Before understanding the types and patterns of fever, it is essential to know its phases.
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Methods of reducing fever01:22

Methods of reducing fever

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The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
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Coordination Compounds and Nomenclature02:54

Coordination Compounds and Nomenclature

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In most main group element compounds, the valence electrons of the isolated atoms combine to form chemical bonds that satisfy the octet rule. For instance, the four valence electrons of carbon overlap with electrons from four hydrogen atoms to form CH4. The one valence electron leaves sodium and adds to the seven valence electrons of chlorine to form the ionic formula unit NaCl (Figure 1a). Transition metals do not normally bond in this fashion. They primarily form coordinate covalent bonds, a...
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Histone Modification02:32

Histone Modification

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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone...
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Euchromatin01:01

Euchromatin

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The extent of chromatin compaction can be studied by staining chromatin using specific DNA binding dyes. Under the microscope, the dense-compacted regions take up more dye, appearing darker, while the less-compact areas take up less dye and appear lighter. Based on the compaction level, chromatins are classified into two primary forms – euchromatin and heterochromatin.
Euchromatin is the less dense region of the chromatin and stains lighter. Euchromatin contains histone H3 extensively...
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Updated: Feb 14, 2026

Preventing the Spread of Malaria and Dengue Fever Using Genetically Modified Mosquitoes
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Tri-phasic fever in dengue fever.

Pradeepa H D1, Sathish B Rao2, Ganaraj B3

  • 11 PhD Scholar, Department of Internal Medicine, 76798 Kasturba Medical College , Manipal Academy of Higher Education, Manipal, Mangaluru, India.

Tropical Doctor
|February 9, 2018
PubMed
Summary

Dengue fever often shows a tri-phasic temperature pattern, unlike other fevers. Continuous temperature monitoring can help doctors quickly distinguish dengue fever from other febrile illnesses.

Keywords:
24 hoursContinuousconventional monitoringdengue fevertemperature peak

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Area of Science:

  • Infectious Diseases
  • Clinical Medicine
  • Biomedical Engineering

Background:

  • Dengue fever is a significant global health concern, presenting as an acute febrile illness.
  • Early and accurate diagnosis of dengue fever is crucial for effective patient management and preventing complications.
  • Distinguishing dengue fever from other febrile illnesses based solely on clinical presentation can be challenging.

Purpose of the Study:

  • To investigate the 24-hour continuous tympanic temperature patterns in patients with dengue fever.
  • To compare these temperature patterns with those of patients experiencing fever from non-dengue etiologies.
  • To assess the utility of continuous temperature monitoring in differentiating dengue fever.

Main Methods:

  • An observational study was conducted involving 15 patients diagnosed with dengue fever.
  • Continuous 24-hour tympanic temperature monitoring was performed on dengue fever patients.
  • Temperature patterns were compared between dengue fever patients and a control group of 26 patients with non-dengue fever.

Main Results:

  • A tri-phasic fever pattern was observed in approximately two-thirds of dengue fever patients.
  • This tri-phasic pattern was rarely seen in patients with non-dengue fever, with only one case in an inflammatory condition.
  • One-third of dengue fever patients presented with a single peak temperature pattern.
  • Continuous temperature monitoring revealed distinct patterns differentiating dengue fever.

Conclusions:

  • Continuous temperature monitoring and analysis of fever patterns can aid in the early differentiation of dengue fever.
  • The tri-phasic fever pattern is a potential indicator for identifying dengue fever.
  • This method offers a valuable tool for clinicians in distinguishing dengue fever from other febrile conditions, improving diagnostic accuracy.