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Programmed oocyte retrieval during routine laparoscopy and embryo cryopreservation for later transfer
American Journal of Obstetrics and Gynecology
|July 1, 1986
Summary
Fixed-schedule ovulation induction and embryo cryopreservation offer an additional pregnancy opportunity for women undergoing laparoscopy for infertility. This approach successfully yielded pregnancies, providing a valuable option before in vitro fertilization.
Area of Science:
- Reproductive Medicine
- Gynecology
- Embryology
Background:
- Infertility investigation often involves diagnostic laparoscopy.
- Integrating fertility treatments during laparoscopy can optimize patient care.
- Ovarian stimulation and embryo cryopreservation are established fertility techniques.
Purpose of the Study:
- To evaluate the feasibility of fixed-schedule ovulation induction and embryo cryopreservation in women undergoing laparoscopy for infertility.
- To assess the pregnancy outcomes following embryo transfer from cryopreserved embryos obtained during this procedure.
Main Methods:
- Women undergoing laparoscopy for infertility received a modified hormonal cycle (progestogen or estrogen-progestogen pill) prior to follicular stimulation.
- Oocyte retrieval was performed, and resulting embryos were cryopreserved.
- A control group undergoing standard in vitro fertilization was used for comparison of oocyte yield.
Main Results:
- Oocytes were obtained in 29 of 30 patients (96.7%) where ovarian access was possible.
- One or more embryos were obtained in 22 of 30 patients (73.3%).
- Six pregnancies were initiated after thawing and transferring 25 embryos from 17 patients; three are ongoing.
Conclusions:
- Programmed oocyte retrieval and embryo cryopreservation during laparoscopy is a viable strategy.
- This approach provides an additional chance for pregnancy in women undergoing infertility investigations.
- The technique offers a valuable adjunct to standard infertility management pathways.