Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Filtration and Urine Formation01:32

Filtration and Urine Formation

53.9K
The function of the kidneys is to filter, reabsorb, secrete, and excrete. Every day the kidneys filter nearly 180 liters of blood, initially removing water and solutes but ultimately returning nearly all filtrates into circulation with the help of osmoregulatory hormones. This process removes wastes and toxins but is also crucial to maintain water and electrolyte levels. Most of these functions are performed by the tiny but numerous nephrons contained within the kidneys.
53.9K
Urine Studies II: Urine Culture and Sensitivity Test01:26

Urine Studies II: Urine Culture and Sensitivity Test

1.3K
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
1.3K
Bacterial Phylum Chlamydiae01:29

Bacterial Phylum Chlamydiae

601
The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
601
Urine Studies I: Urinalysis01:29

Urine Studies I: Urinalysis

1.6K
Urinalysis is a widely used diagnostic test that analyzes urine's physical, chemical, and microscopic characteristics. Healthcare providers use it to detect and monitor various health conditions, including renal disease, urinary tract infections (UTIs), diabetes, and metabolic or systemic disorders.Components of UrinalysisUrinalysis consists of three primary components: physical, chemical, and microscopic examination. Each provides unique insights into the urine sample and, by extension, the...
1.6K
Physiology of Urine Formation01:24

Physiology of Urine Formation

13.3K
Urine formation is an essential function of the human body. It plays a critical role in maintaining homeostasis by regulating the volume and composition of body fluids. The kidneys, the primary organs involved in this process, filter blood to remove waste products and excess substances, ultimately producing urine.
Glomerular Filtration
The first stage in urine formation is glomerular filtration. Each kidney contains approximately 1 million nephrons, the functional units of filtration, with a...
13.3K
Formation of Concentrated Urine01:23

Formation of Concentrated Urine

3.6K
There is a gradient of solutes in the interstitial fluid from the renal cortex through the medulla, known as the medullary osmotic gradient. The juxtamedullary nephrons establish and maintain this gradient using countercurrent mechanisms with loops extending deep into the medulla. These nephrons also use countercurrent mechanisms to regulate urine volume and concentration. The interaction between the descending and ascending limbs of the nephron loop creates an osmotic gradient through...
3.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Experiences of Trans and Gender Diverse Youth Accessing Emergency Departments: Results of a Community-Designed Questionnaire.

Journal of emergency nursing·2026
Same author

Evaluating the MedMira Multiplo® Complete Syphilis (TP/nTP) antibody test in a sexually transmitted infection clinic in Ottawa, Canada: increased rapid diagnosis and improved antibiotic stewardship.

BMC infectious diseases·2025
Same author

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2025
Same author

Canadian guideline on HIV pre- and postexposure prophylaxis: 2025 update.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2025
Same author

Comparing the Uptake of HIV Self-Testing to HIV Serology: Findings from GetaKit-A Prospective Open Cohort Study in Ontario, Canada.

Journal of the International Association of Providers of AIDS Care·2025
Same author

Should we still treat asymptomatic <i>Neisseria gonorrhoeae</i> and <i>Chlamydia trachomatis</i> contacts in the era of NAATs? Reviewing data from the GetaKit study to inform practice.

Sexually transmitted infections·2025

Related Experiment Video

Updated: Feb 14, 2026

Forward Genetic Approaches in Chlamydia trachomatis
09:03

Forward Genetic Approaches in Chlamydia trachomatis

Published on: October 23, 2013

13.3K

Overfilled urine specimens for gonorrhea and chlamydia testing: Implications for practice.

Patrick O'Byrne1, Lauren Orser1

  • 1University of Ottawa, 451 Smyth Road, K1h 8M5 Ottawa, ON, Canada.

Applied Nursing Research : ANR
|February 10, 2018
PubMed
Summary

When patients provide overfilled urine samples for sexually transmitted infection (STI) testing, submitting the sample and asking patients to retest can maximize infection detection rates. This approach balances diagnostic yield with patient follow-up challenges.

Keywords:
ChlamydiaGonorrheaScreeningSexually transmitted infectionsUrine

More Related Videos

Crack Monitoring in Resonance Fatigue Testing of Welded Specimens Using Digital Image Correlation
05:30

Crack Monitoring in Resonance Fatigue Testing of Welded Specimens Using Digital Image Correlation

Published on: September 29, 2019

8.7K
Micromechanical Tension Testing of Additively Manufactured 17-4 PH Stainless Steel Specimens
05:38

Micromechanical Tension Testing of Additively Manufactured 17-4 PH Stainless Steel Specimens

Published on: April 7, 2021

3.9K

Related Experiment Videos

Last Updated: Feb 14, 2026

Forward Genetic Approaches in Chlamydia trachomatis
09:03

Forward Genetic Approaches in Chlamydia trachomatis

Published on: October 23, 2013

13.3K
Crack Monitoring in Resonance Fatigue Testing of Welded Specimens Using Digital Image Correlation
05:30

Crack Monitoring in Resonance Fatigue Testing of Welded Specimens Using Digital Image Correlation

Published on: September 29, 2019

8.7K
Micromechanical Tension Testing of Additively Manufactured 17-4 PH Stainless Steel Specimens
05:38

Micromechanical Tension Testing of Additively Manufactured 17-4 PH Stainless Steel Specimens

Published on: April 7, 2021

3.9K

Area of Science:

  • Clinical diagnostics
  • Public health
  • Microbiology

Background:

  • Specimen collection guidelines are crucial for accurate diagnostic testing.
  • Deviations from guidelines, such as overfilled urine samples for sexually transmitted infections (STIs), present clinical challenges.
  • Limited research exists on managing overfilled samples in STI testing.

Purpose of the Study:

  • To evaluate the feasibility and diagnostic yield of submitting overfilled urine samples for STI testing.
  • To determine the outcomes of STI testing on samples exceeding 30mL.
  • To inform clinical practice regarding the management of non-compliant urine specimens.

Main Methods:

  • Retrospective review of clinical data over a 6-month period.
  • Tracking of urine sample volume, STI test results, and patient return rates for retesting.
  • Analysis of infection positivity rates for chlamydia and gonorrhea.

Main Results:

  • 33 patients provided overfilled urine samples; 70% (n=23) were submitted for testing.
  • Submitted samples identified 5 infections in 4 patients (17.4% chlamydia, 4.3% gonorrhea).
  • Only 60% of patients advised to retest returned for follow-up.

Conclusions:

  • Submitting overfilled urine samples may detect infections despite guideline violations.
  • Potential for false negatives exists, necessitating careful interpretation.
  • Recommending retesting for patients with overfilled samples can improve diagnostic rates, but adherence is a concern.