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Bone loss in women with BRCA1 and BRCA2 mutations

C Bethan Powell1, Amy Alabaster2, Nicole Stoller2

  • 1Kaiser Permanente Northern California Gynecologic Cancer Program, San Francisco, CA, USA; Kaiser Permanente Northern California, Division of Research, Oakland, CA, USA.

Gynecologic Oncology
|February 10, 2018
PubMed
Summary

Bone loss is common in women with BRCA mutations, especially after risk-reducing salpingo-oophorectomy (RRSO). Higher BMI and non-white race were protective, while older age and SERM use increased bone loss risk.

Keywords:
Bone lossGeneticsOophorectomy

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