Extended cold snare polypectomy for small colorectal polyps increases the R0 resection rate

Area of Science:

• Gastroenterology
• Endoscopic Surgery
• Colorectal Cancer Prevention

Background:

• Cold snare polypectomy (CSP) is widely used for colorectal polyp removal.
• Data on the R0 resection rate (complete tumor removal) with CSP is limited.
• Extended CSP involves resecting polyps with a circumferential margin >1mm.

Purpose of the Study:

• To compare the R0 resection rate of extended CSP versus conventional CSP.
• To evaluate the safety of extended CSP in terms of complications.

Main Methods:

• Retrospective analysis of 712 non-pedunculated colorectal polyps (<10mm) from 316 patients.
• Polyps were resected using either conventional CSP or extended CSP.
• Comparison of R0 resection rates and complication rates between the two groups.

Main Results:

• The R0 resection rate was significantly higher with extended CSP (98%) compared to conventional CSP (84%).
• No significant differences in baseline patient or polyp characteristics were observed between groups.
• No delayed bleeding or perforation occurred in either the conventional or extended CSP groups.

Conclusions:

• Extended CSP achieves a higher R0 resection rate than conventional CSP for colorectal polyps <10mm.
• Extended CSP is a safe endoscopic resection technique, with no increased risk of delayed bleeding or perforation.
• Extended CSP is a promising method for complete endoscopic removal of non-pedunculated colorectal polyps.