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Molecular Evolution of the Tre Recombinase
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Developmental plasticity: Bridging research in evolution and human health.
Amanda J Lea1, Jenny Tung1,2,3,4, Elizabeth A Archie2,5
1Department of Biology, Duke University, Durham, NC 27708, USA.
Evolution, Medicine, and Public Health
|February 10, 2018
Summary
Early life experiences shape lifelong traits through developmental plasticity. Understanding its evolutionary and genetic basis can improve human health and evolutionary biology insights.
Area of Science:
- Evolutionary Biology
- Human Health
- Developmental Biology
Background:
- Early life experiences significantly influence lifelong traits, impacting behavior, disease risk, and mortality.
- Developmental plasticity, the adaptation of traits to early environments, is observed in humans and animals.
- Interdisciplinary research on developmental plasticity offers a unified understanding.
Purpose of the Study:
- To bridge evolutionary biology and human health research on developmental plasticity.
- To identify shared questions and interdisciplinary approaches for studying developmental plasticity.
- To foster a comprehensive understanding of developmental plasticity across diverse fields.
Main Methods:
- Reviewing evolutionary explanations for developmental plasticity.
- Examining the genetic underpinnings of developmental plasticity.
- Investigating the molecular mechanisms mediating developmental plasticity.
Main Results:
- Highlights key questions in evolutionary biology and human health regarding developmental plasticity.
- Identifies theories and empirical work addressing these shared questions.
- Emphasizes conceptual gains from interdisciplinary approaches.
Conclusions:
- Filling knowledge gaps in developmental plasticity offers mutual benefits for human health and evolutionary biology.
- Encourages researchers to integrate insights from diverse fields.
- Aims to establish a cross-disciplinary understanding of developmental plasticity.
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