Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multiple Allele Traits01:49

Multiple Allele Traits

38.2K
The Concept of Multiple Allelism
38.2K
Multiple Regression01:25

Multiple Regression

4.0K
Multiple regression assesses a linear relationship between one response or dependent variable and two or more independent variables. It has many practical applications.
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...
4.0K
Multiple Voltage Sources01:25

Multiple Voltage Sources

1.8K
Generally, a single battery is not enough to power some devices. In such cases, batteries can be combined in two ways: in series or in parallel.
In series, the positive terminal of one battery is connected to the negative terminal of another battery. Hence, the voltage of each battery is added to give the net voltage, which is increased because each battery boosts the electrons that enter it. The same current flows through each battery because they are connected in series.
Batteries are...
1.8K
Deformation of Member under Multiple Loadings01:11

Deformation of Member under Multiple Loadings

497
When a rod is made of different materials or has various cross-sections, it must be divided into parts that meet the necessary conditions for determining the deformation. These parts are each characterized by their internal force, cross-sectional area, length, and modulus of elasticity. These parameters are then used to compute the deformation of the entire rod.
In the case of a member with a variable cross-section, the strain is not constant but depends on the position. The deformation of an...
497
Multiple Bar Graph01:07

Multiple Bar Graph

10.2K
As the name suggests, a multiple bar graph is the same as a bar graph but has multiple bars to depict relationships between different data values. One can include as many parameters as possible. However, each parameter must have the same unit of measurement.
Each bar or column in the multiple bar graph represents a data value. These graphs are used primarily in interrelating two or more sets of data. The categories of different kinds of data are listed along the horizontal or x-axis, whereas...
10.2K
Multiple Comparison Tests01:13

Multiple Comparison Tests

4.5K
Multiple comparison test, abbreviated as MCT, is a post hoc analysis generally performed after comparing multiple samples with one or more tests. An MCT will help identify a significantly different sample among multiple samples or a factor among multiple factors.
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
4.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diffuse Large B Cell Lymphoma: Immunohistochemical Classification According to Hans Algorithm and Association With Outcome in A Moroccan Institution.

Clinical pathology (Thousand Oaks, Ventura County, Calif.)·2024
Same author

[Extensive cutaneous necrosis].

La Revue de medecine interne·2023
Same author

Prevalence and antibiotic resistance profiles of Staphylococcus sp. isolated from food, food contact surfaces and food handlers in a Moroccan hospital kitchen.

Letters in applied microbiology·2020
Same author

A three-dimensional geometric quantification of human cortical canals using an innovative method with micro-computed tomographic data.

Micron (Oxford, England : 1993)·2018
Same author

Dairy products and colorectal cancer in middle eastern and north African countries: a systematic review.

BMC cancer·2018
Same author

[Syndrome lymphohistiocytic activation: the glass half full or empty? Reply].

Annales francaises d'anesthesie et de reanimation·2014

Related Experiment Video

Updated: Feb 14, 2026

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
09:41

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells

Published on: July 15, 2015

9.1K

[Digital ischemia revealing multiple myeloma].

Z Khammar1, M Ouazzani1, B Bennani1

  • 1Service de médecine interne, CHU Hassan II, Fès, Maroc.

Journal De Medecine Vasculaire
|February 10, 2018
PubMed
Summary

Digital ulcers and necrosis in men, often linked to vascular disease, can rarely signal paraneoplastic syndromes. This case highlights Kahler disease as a potential cause, emphasizing the need to investigate blood disorders and cancer when typical causes are excluded.

Keywords:
CryoglobulinsCryoglobulinémieDigital necrosisDigital ulcerMultiple myelomaMyélome multipleNécrose digitaleUlcère digital

More Related Videos

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma
07:53

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma

Published on: April 15, 2022

4.8K
Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
10:04

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

Published on: May 1, 2015

13.5K

Related Experiment Videos

Last Updated: Feb 14, 2026

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
09:41

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells

Published on: July 15, 2015

9.1K
Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma
07:53

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma

Published on: April 15, 2022

4.8K
Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
10:04

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

Published on: May 1, 2015

13.5K

Area of Science:

  • Vascular Medicine
  • Oncology
  • Hematology

Background:

  • Digital ulcers typically result from microangiopathy-related focal ischemia.
  • In men, causes include diffuse arterial disease (e.g., Leo-Buerger) or emboligenic heart disease.
  • Paraneoplastic digital necrosis is a rare etiology.

Observation:

  • A 75-year-old man presented with digital cyanosis and pulp ulcers.
  • Necrotic damage progressed distally without other symptoms.
  • Blood tests indicated Kahler disease; cryoglobulin test was positive.

Findings:

  • Chemotherapy led to clinical improvement.
  • The case illustrates a rare paraneoplastic presentation of digital necrosis.
  • Exclusion of common causes necessitates investigation for hematologic malignancies.

Implications:

  • Distal necrotic damage warrants investigation for underlying blood disorders or cancer.
  • Early diagnosis of paraneoplastic digital necrosis can guide timely cancer treatment.
  • This case expands the differential diagnosis for digital ischemia in men.