[SSC International Guideline 2016 - Management of Sepsis and Septic Shock]

The new guideline of the Surviving Sepsis Campaign was revised in 2016 and presented in 2017. Furthermore, "Sepsis-3" in 2016 completely changed the definition of Sepsis from inflammation plus infection to a "life-threatening organ dysfunction caused by a dysregulated host response". To cope with the great challenge to unite the new evidence of sepsis treatment with the new definition of sepsis, the guidelines have been completely reconstructed and comprehensively deal with new evidence. The guidelines discuss sepsis-specific treatment and provide recommendations on general measures of intensive care for sepsis. The article summarizes the most important recommendations and additionally discusses some crucial amendments. This is intended to encourage the reader to incorporate the new guideline into clinical practice, thus improving the prognosis of patients suffering from sepsis or septic shock.