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Hepatobiliary phase liver MR imaging findings after Oxaliplatin-based chemotherapy in cancer patients
Emre Ünal1, Ali Devrim Karaosmanoğlu1, Mustafa Nasuh Ozmen1
1Liver Imaging Team, Department of Radiology, Hacettepe University School of Medicine, 06100, Ankara, Turkey.
Objective:
To describe Gd-EOB-DTPA-enhanced liver MR imaging findings in colon and rectal cancer patients who received Oxaliplatin.
Conclusion:
Spectrum of hepatobiliary phase imaging findings include diffuse heterogeneous dysfunction, macronodular and micronodular FNH-like lesions, and coexistence of periportal increased liver function with FNH-like lesions. Differentiation of these benign lesions from metastasis is crucial to avoid biopsy in patients with colorectal cancers and may allow better understanding of sinusoidal obstruction syndrome pathophysiology and regenerative response of liver.
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