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Updated: Feb 14, 2026
06:09
Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
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Severe hantavirus disease in children
Tamara K Dzagurova1, Evgeniy A Tkachenko2, Aydar A Ishmukhametov2
1Chumakov Federal Scientific Center for Research and Development of Immune-and Biological Products of Russian Academy of Sciences, Moscow, Russia.
Summary
Sochi virus causes severe hantavirus disease. Children infected with this novel European hantavirus experience clinical courses comparable to adults, highlighting the need for vigilance in endemic areas.
Area of Science:
- Virology
- Infectious Diseases
- Pediatrics
Background:
- A novel European hantavirus, Sochi virus, has been identified.
- Sochi virus infection is associated with severe hantavirus disease and a 15% case fatality rate.
Purpose of the Study:
- To investigate the prevalence and clinical severity of Sochi virus infection in children.
- To compare the clinical presentation of hantavirus disease in pediatric patients versus adults.
Main Methods:
- Molecular, serological, and epizoonotic studies confirmed Sochi virus infections.
- Clinical and laboratory data were analyzed for children (up to 15 years) and adult patients.
Main Results:
- Children (up to 15 years) represented 9.7% (6/62) of the studied hantavirus disease patients.
- Pediatric patients exhibited moderate to severe clinical courses, similar to adult patients.
Conclusions:
- Despite general perceptions, children infected with highly pathogenic hantaviruses like Sochi virus show comparable disease severity to adults.
- Hantavirus disease should be considered in children presenting with unexplained fever and kidney or pulmonary failure, especially in endemic regions.
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