Related Experiment Video

Updated: Feb 14, 2026

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

1.2K

[Effect of vitamin A as an adjuvant therapy for pneumonia in children: a Meta analysis]

Nan Hu1, Qu-Bei Li, Shan-Ye Zou

  • 1Department of Pneumology, Children's Hospital of Chongqing Medical University/Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders/Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China. liqubei@126.com.

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics
|February 13, 2018
PubMed

Insights

Vitamin A supplementation for children with pneumonia improves clinical response and shortens recovery time without increasing adverse effects. This review highlights vitamin A

Area of Science:

  • Pediatric Pulmonology
  • Nutritional Science
  • Evidence-Based Medicine

Background:

  • Pneumonia is a leading cause of childhood mortality globally.
  • Vitamin A deficiency is common in children with pneumonia.
  • The role of vitamin A as an adjuvant therapy for pneumonia requires clarification.

Purpose of the Study:

  • To systematically review and meta-analyze randomized controlled trials (RCTs) investigating the efficacy and safety of vitamin A supplementation in children with pneumonia.

Main Methods:

  • Comprehensive literature search across multiple databases (Cochrane Library, EMbase, PubMed, etc.).
  • Inclusion of 15 RCTs involving 3,021 pediatric patients.
  • Meta-analysis performed using RevMan5.3 software.

Main Results:

  • Vitamin A supplementation did not significantly reduce pneumonia-related mortality.
  • It significantly increased the overall clinical response rate.
  • It shortened the duration of fever, cough, abnormal chest X-ray findings, and hospital stay.

Conclusions:

  • Vitamin A as an adjuvant therapy effectively alleviates clinical symptoms and signs in pediatric pneumonia.
  • It contributes to a reduced length of hospital stay.
  • No increased incidence of adverse reactions was observed with vitamin A supplementation.
Abstract

More Related Videos

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia04:34

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia

Published on: February 17, 2023

1.7K
Oral Biofilm Sampling for Microbiome Analysis in Healthy Children10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

17.9K

Related Concept Videos

Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
2.5K
Pedigree Analysis01:35

Pedigree Analysis

Overview
89.9K
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
932
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
3.1K
Directing Effect of Substituents: meta-Directing Groups01:09

Directing Effect of Substituents: meta-Directing Groups

Substituents on the benzene ring that direct an incoming electrophile to undergo substitution at the meta position are called meta directors. All meta directors either have a positive charge on the atom directly bonded to the ring or a partial positive charge. These groups function by withdrawing electrons from the ring through inductive and resonance effects. Consider the carbocation intermediates formed upon the addition of an electrophile on nitrobenzene at the...
6.1K
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
835