Aging in HIV-Infected Subjects: A New Scenario and a New View

Area of Science:

• Geriatrics
• Infectious Diseases
• Public Health

Background:

• The population of individuals aged 50 years and older living with HIV (human immunodeficiency virus) is rapidly expanding, projected to reach 73% by 2030.
• HIV-infected individuals face a higher prevalence of comorbidities and age-related conditions, including geriatric syndromes, functional impairments, neurocognitive/mental health issues, polypharmacy, and social difficulties, compared to their uninfected peers.

Purpose of the Study:

• To examine age-related conditions prevalent in older adults with HIV.
• To provide guidance on optimal clinical management strategies for this growing demographic.
• To highlight the need for more research on less-studied aspects like psychological, social, and functional screening.

Main Methods:

• Review of author expertise and published literature on age-related conditions in HIV.
• Analysis of the increased vulnerability of HIV-infected individuals to geriatric syndromes and associated challenges.
• Identification of gaps in current knowledge regarding the clinical management of older adults with HIV.

Main Results:

• Older adults with HIV exhibit a higher burden of comorbidities and age-related conditions.
• Existing clinical management guidelines may not adequately address the unique needs of this population.
• There is a significant lack of information on optimal screening and management for psychological, social, and functional capabilities in this group.

Conclusions:

• Effective clinical management for older adults with HIV requires a comprehensive approach addressing multiple age-related conditions.
• Further research and evidence-based guidelines are crucial to optimize care for the aging HIV population.
• Proactive screening for psychological, social, and functional status is essential for holistic patient care.