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Gene Expression Dominance in Allopolyploids: Hypotheses and Models
Samuel Bottani1, Nicolae Radu Zabet2, Jonathan F Wendel3
1Matière et Systèmes Complexes, UMR 7057, Paris 75013, France; Université Paris Diderot-Paris VII, 75205 Paris Cedex 13, France; These authors contributed equally to this work.
Abstract:
The classical example of nonadditive contributions of the two parents to allopolyploids is nucleolar dominance, which entails silencing of one parental set of ribosomal RNA genes. This has been observed for many other loci. The prevailing explanation for this genome-wide expression disparity is that the two merged genomes differ in their transposable element (TE) complement and in their level of TE-mediated repression of gene expression. Alternatively, and not exclusively, gene expression dominance may arise from mismatches between trans effectors and their targets. Here, we explore quantitative models of regulatory mismatches leading to gene expression dominance. We also suggest that, when pairs of merged genomes are similar from one allopolyploidization event to another, gene-level and genome dominance patterns should also be similar.
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