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Exogenous human herpesvirus 6 reinfection after tumor-infiltrating T-lymphocyte therapy
Anastasiia Filippova1, Julie Charles2, Olivier Epaulard3
1Laboratory of Virology, University Hospital of Grenoble, Grenoble, France; Irkutsk State Medical University, Ministry of Health of Russia, Irkutsk, Russia.
Abstract:
Exogenous human herpes virus 6 (HHV-6) reinfection has never been reported in patients receiving tumor-infiltrating T lymphocytes therapy. We report an unusual case of HHV-6 infection following infusion of HHV-6 infected autologous T lymphocytes. HHV-6 infection could interfere with the tumor antigen immune recognition and the efficacy of immunotherapy.
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