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Comprehensive Assessment of Risk Factors of Cause-Specific Infant Deaths in Japan
Yui Yamaoka1, Naho Morisaki2, Haruko Noguchi3
1Department of Health Services Research, Faculty of Medicine, University of Tsukuba.
Insights
Both social and biological risk factors increase infant mortality risk from disease, abuse, and accidents. Addressing these factors requires integrated public health and clinical support for vulnerable infants.
Area of Science:
- Public Health
- Pediatrics
- Sociology
Background:
- Infants with high social risk (e.g., child abuse) and biological risk (e.g., disease) receive separate attention.
- Limited research exists on the combined impact of social and biological factors on cause-specific infant mortality.
Purpose of the Study:
- To investigate the associations between biological and social risk factors and infant mortality.
- To examine cause-specific infant mortality, including medical (internal), abuse (intentional external), and accident (unintentional external) causes.
Main Methods:
- Utilized Japanese national vital statistics data (2003-2010) linking birth and death records.
- Employed multivariate logistic regression to analyze the relationship between risk factors and infant mortality outcomes.
Main Results:
- Over 8.9 million births showed 23,400 infant deaths (0.26%) within the first year.
- High social risk factors (e.g., teenage mothers, single mothers) were linked to increased mortality from internal, intentional external, and unintentional external causes.
- Biological factors like small for gestational age and preterm birth increased risks for internal and unintentional external cause deaths, but not intentional external causes.
Conclusions:
- Both biological and social factors significantly influence infant mortality across different causes.
- Integrated support from public health and clinical professionals is crucial for preventing infant deaths in high-risk populations.
Background:
Public attention is given to infants with socially high risks of child abuse and neglect, while clinical attention is provided to infants with a biologically high risk of diseases. However, few studies have systematically evaluated how biological or social factors cross over and affect cause-specific infant mortality.
Methods:
We linked birth data with death data from the Japanese national vital statistics database for all infants born from 2003-2010. Using multivariate logistic regression, we examined the association between biological and social factors and infant mortality due to medical causes (internal causes), abuse (intentional external causes), and accidents (unintentional external causes).
Results:
Of 8,941,501 births, 23,400 (0.26%) infants died by 1 year of age, with 21,884 (93.5%) due to internal causes, 175 (0.75%) due to intentional external causes, and 1,194 (5.1%) due to unintentional external causes. Infants with high social risk (teenage mothers, non-Japanese mothers, single mothers, unemployed household, four or more children in the household, or birth outside of health care facility) had higher risk of death by intentional, unintentional, and internal causes. Infant born with small for gestational age and preterm had higher risks of deaths by internal and unintentional causes, but not by intentional causes.
Conclusions:
Both biological as well as social factors were associated with infant deaths due to internal and external causes. Interdisciplinary support from both public health and clinical-care professionals is needed for infants with high social or biological risk to prevent disease and injury.
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