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Updated: Feb 14, 2026

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
Published on: October 2, 2015
Controlling mechanism of absence seizures by deep brain stimulus applied on subthalamic nucleus
Bing Hu1, Yu Guo1, Xiaoqiang Zou1
1Institute of Applied Mathematics, Department of Mathematics and Statistics, College of Science, Huazhong Agricultural University, Wuhan, 430070 China.
Abstract:
Based on a classical model of the basal ganglia thalamocortical network, in this paper, we employed a type of the deep brain stimulus voltage on the subthalamic nucleus to study the control mechanism of absence epilepsy seizures. We found that the seizure can be well controlled by turning the period and the duration of current stimulation into suitable ranges. It is the very interesting bidirectional periodic adjustment phenomenon. These parameters are easily regulated in clinical practice, therefore, the results obtained in this paper may further help us to understand the treatment mechanism of the epilepsy seizure.
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