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Updated: Feb 14, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
A novel diterpenoid with a rearranged neoclerodane skeleton from Salvia leucantha CAV
Yuji Narukawa1, Keiichiro Hatano2, Tadahiro Takeda3
1Kyoritsu University of Pharmacy, Shibakoen 1-5-30, Minato-ku, Tokyo 105-8512, Japan.
Abstract:
A new diterpenoid with a rearranged neoclerodane skeleton, spiroleucantholide (compound "S1"), along with four known diterpenoids-salvifaricin (compound "S2"), isosalvipuberulin (compound "S3"), salvileucantholide (compound "S4"), and salviandulin E (compound "S5")-was isolated from the aerial parts of Salvia leucantha CAV.. The structures were established by spectroscopic methods, including the X-ray analysis of spiroleucantholide (S1).
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