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Improving medication-related clinical decision support.

Clare L Tolley1, Sarah P Slight2,3, Andrew K Husband4

  • 1Institute of Health and Society, Sir James Spence Institute, Newcastle University, Newcastle upon Tyne, United Kingdom, United Kingdom.

American Journal of Health-System Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
|February 14, 2018
PubMed
Summary
This summary is machine-generated.

Medication-related clinical decision support (CDS) systems need improvement for better alert value and actionability. Enhancing specificity, integrating patient data, and considering human factors are key to optimizing CDS effectiveness.

Keywords:
clinicaldecision support systemsdecision-makingelectronic prescribingmedical order entry systemsmedication errorspatient safety

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Area of Science:

  • Health Informatics
  • Clinical Pharmacy
  • Medical Decision Support

Background:

  • Medication-related clinical decision support (CDS) systems are crucial for safe medication use.
  • Current systems face challenges in alert value and user actionability.
  • Optimizing CDS requires addressing system limitations and enhancing user experience.

Purpose of the Study:

  • To review current uses of medication-related CDS.
  • To identify recommendations for improving these systems.
  • To analyze the effectiveness of 5 core CDS functionalities.

Main Methods:

  • Systematic review of articles from MEDLINE and EMBASE (2007-2014).
  • Keywords focused on 5 medication-related CDS functionalities: drug-drug interaction (DDI) checks, drug allergy checks, drug dose support, drug duplication checks, and drug formulary support.
  • Analysis of 156 full-text articles and 28 conference abstracts.

Main Results:

  • Success hinges on users finding alerts valuable and acting on them.
  • Improving alert specificity and sensitivity is crucial across all CDS domains.
  • Specific improvements include tiering for DDI alerts, cross-sensitivity for allergy checks, individualized dosing, toxicity prevention for duplication checks, and accurate databases for formulary support.

Conclusions:

  • Medication-related CDS is immature in many organizations, with significant room for enhancement.
  • Integrating patient-specific factors and human factors principles is essential.
  • Standardization and improved alert specificity are vital for realizing CDS potential and reducing alert fatigue.