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Complete Genome Sequences of 44 Arthrobacter Phages
Karen K Klyczek1, Deborah Jacobs-Sera2, Tamarah L Adair3
1Department of Biology, University of Wisconsin-River Falls, River Falls, Wisconsin, USA.
Genome Announcements
|February 14, 2018
Summary
Researchers sequenced 44 bacteriophages infecting Arthrobacter bacteria. These double-stranded DNA viruses exhibit diverse genome sizes and G+C content, representing all three major tail types.
Area of Science:
- Microbiology
- Virology
- Genomics
Background:
- Bacteriophages are viruses that infect bacteria and play crucial roles in microbial ecosystems.
- Arthrobacter species are common soil bacteria with implications in various environmental and industrial processes.
- Understanding phage diversity is essential for phage therapy and microbial community dynamics.
Purpose of the Study:
- To determine the complete genome sequences of 44 novel bacteriophages.
- To characterize the genomic properties of these phages infecting Arthrobacter sp. strain ATCC 21022.
- To provide a comprehensive genomic resource for Arthrobacter-infecting phages.
Main Methods:
- Whole-genome sequencing of isolated bacteriophages.
- Bioinformatic analysis of genome size, G+C content, and gene content.
- Phylogenetic analysis to determine phage relationships.
Main Results:
- Complete genome sequences for 44 Arthrobacter-infecting phages were obtained.
- Genome sizes ranged from 15,680 to 70,707 base pairs.
- G+C content varied from 45.1% to 68.5%, encompassing all three major phage tail morphologies (Siphoviridae, Myoviridae, Podoviridae).
Conclusions:
- The study presents a significant expansion of the genomic data available for Arthrobacter phages.
- The characterized phages represent a diverse group with potential applications in biotechnology and phage therapy.
- These findings contribute to our understanding of phage-host interactions and phage evolution within the Arthrobacter genus.
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