Related Experiment Video
Updated: Feb 14, 2026

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit
Published on: May 14, 2020
Morphological characteristics associated with the rupture risk of mirror posterior communicating artery aneurysms
Guang-Xian Wang1, Jun Liu2, You-Qiang Chen3
1Department of Radiology, Xinqiao Hospital, Third Military Medical University, Chongqing, China.
Objective:
Patient related clinical factors and intracranial aneurysms (IAs) at different locations may lead to statistical bias when investigating the rupture risk of IAs. Thus the purpose of this study was to identify the morphological parameters that are related to the rupture of mirror posterior communicating artery aneurysms (PComAAs).
Methods:
Between August 2011 and July 2017, 68 patients with mirror PComAAs and aneurysmal subarachnoid hemorrhage were diagnosed by CT angiography at three medical centers. Morphological characteristics for PComAAs included bifurcation, shape, neck width, width, depth, maximum size, flow angle, parent vessel diameter, aspect ratio (AR), depth/width ratio, bottleneck factor, and size ratio (SR). Multiple logistic regression analysis was performed to determine the independent risk factors for rupture. Receiver operating characteristic curve analysis was performed to obtain the optimal thresholds.
Results:
AR (OR 5.623) and SR (OR 5.570) were more commonly observed in the ruptured cohort. The threshold values of AR and SR were 0.98 and 1.21, respectively.
Conclusions:
Mirror PComAAs are a useful model to investigate the rupture risk of PComAAs. AR (≥0.98) and SR (≥1.21) are better predictors of ruptured PComAAs.
Insights
Aspect ratio (AR) and size ratio (SR) are key predictors for ruptured posterior communicating artery aneurysms (PComAAs). These morphological parameters, specifically AR ≥ 0.98 and SR ≥ 1.21, can help identify rupture risk in PComAAs.
Area of Science:
- Neurosurgery
- Medical Imaging
- Biomedical Engineering
Background:
- Intracranial aneurysms (IAs) pose a rupture risk.
- Patient-related factors and IA location can introduce bias in rupture risk studies.
- Mirror posterior communicating artery aneurysms (PComAAs) offer a specific model for investigating rupture.
Purpose of the Study:
- To identify morphological parameters associated with the rupture of mirror PComAAs.
- To differentiate between ruptured and unruptured PComAAs based on morphology.
Main Methods:
- CT angiography was used to diagnose 68 patients with mirror PComAAs.
- Morphological characteristics including aspect ratio (AR) and size ratio (SR) were analyzed.
- Logistic regression and ROC curve analysis identified independent risk factors and optimal thresholds.
Main Results:
- Aspect ratio (AR) and size ratio (SR) were significantly associated with ruptured PComAAs.
- The optimal thresholds for AR and SR predicting rupture were 0.98 and 1.21, respectively.
- AR (OR 5.623) and SR (OR 5.570) showed strong predictive value.
Conclusions:
- Mirror PComAAs serve as a valuable model for studying PComAA rupture risk.
- AR (≥0.98) and SR (≥1.21) are robust predictors of PComAA rupture.
- Morphological analysis of PComAAs can aid in assessing rupture potential.
More Related Videos
Related Concept Videos
Communication
Communication
Characteristics of Life
Relative Risk
Aneurysm I: Introduction
Neuronal Communication

