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Published on: October 13, 2023
MOG-antibody demyelinating diseases: a case of post-partum severe rhombencephalitis and transverse myelitis
D Vecchio1, E Virgilio1, P Naldi1
1Neurology Department, Università del Piemonte Orientale, Azienda Ospedaliera-Universitaria Maggiore della Carità, Novara, Italy.
Introduction:
Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) associated disorders present with a spectrum of clinical pictures including brainstem involvement.
Case Report:
A patient with the sudden onset of a post-partum severe rhombencephalitis causing respiratory failure (12 years after a mild transverse myelitis). Despite the aggressive clinical course, she had an impressive recovery after plasmapheresis, and no further relapses on immunosuppression.
Conclusion:
MOG-IgG disorders could relapse several years after onset and involve brainstem. Good prognosis is possible after treatment.
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