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FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression

Marten Hornsveld1,2, Lydia M M Smits1,2, Maaike Meerlo1,2

  • 1Oncode Institute, University Medical Center Utrecht, Utrecht University, the Netherlands.

Cancer Research
|February 15, 2018
PubMed

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Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
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