Related Experiment Video
Updated: Feb 14, 2026

Experimental Model of Ligature-Induced Peri-Implantitis in Mice
Published on: May 17, 2024
Titanium particles in tissues from peri-implant mucositis: An exfoliative cytology-based pilot study
Shree Lakshmi Deepika Penmetsa1, Rucha Shah1, Raison Thomas1
1Department of Periodontics, Bapuji Dental College and Hospital, Davangere, Karnataka, India.
Background:
To evaluate the presence of titanium particles in the peri-implant mucosa of unloaded single implants.
Materials And Methods:
Forty participants with single unloaded implants were selected. They were divided equally into two groups: Group 1 with mild and Group 2 with moderate-to-severe peri-implant mucositis. Cytologic smears of peri-implant mucosa were obtained using cytobrush during second-stage surgery.
Results:
Study states that 60% of participants of Group 2 were positive for titanium particles in peri-implant cytology.
Conclusion:
This study concludes that the titanium particles might be the initiators of the inflammation around implant.
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