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Author Spotlight: Decellularization-Based Quantification of Skeletal Muscle Fatty Infiltration
Published on: June 9, 2023
Orthopaedic Considerations in the Management of Skeletal Sarcoidosis
Brooke Crawford1, Fadi Badlissi, Santiago A Lozano Calderón
1From the Department of Orthopaedic Surgery, Musculoskeletal Oncology Division, Massachusetts General Hospital, Boston, MA (Dr. Crawford and Dr. Lozano Calderón), the Department of Orthopaedic Surgery (Dr. Crawford) and the Department of Rheumatology (Dr. Badlissi), Beth Israel Deaconess Medical Center, Boston, and the Department of Orthopaedic Surgery, Boston Children's Hospital, Boston (Dr. Crawford).
Abstract:
Advanced imaging has demonstrated that musculoskeletal manifestations of systemic sarcoidosis are more common than previously thought. A definitive strategy for the management of osseous sarcoidosis has not been defined. Some lesions resolve spontaneously, and no systemic medication for sarcoidosis consistently resolves lesions. The orthopaedic surgeon treating patients with musculoskeletal sarcoidosis must make an appropriate diagnosis of bony lesions, seek multidisciplinary input from specialists in pulmonology and rheumatology regarding systemic treatment, and decide when surgery is necessary to prevent dysfunction.
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