Related Experiment Video
Updated: Feb 14, 2026
09:29
Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
Published on: March 20, 2020
19.0K
The relationship between night work and breast cancer
Hye-Eun Lee1, Jongin Lee2, Tae-Won Jang3
11Department of Occupational and Environmental Medicine, Kyung Hee University Hospital, Dongdaemun-gu Kyunghee-daero 23, Seoul, Republic of Korea.
Annals of Occupational and Environmental Medicine
|February 16, 2018
Summary
Night work, a probable human carcinogen, is linked to breast cancer. More research is needed to confirm this association, especially for highly exposed night shift workers, to classify breast cancer as a work-related disease.
Area of Science:
- Occupational Health
- Epidemiology
- Oncology
Background:
- International Agency for Research on Cancer classifies shift work with circadian disruption as a probable human carcinogen.
- Growing concern exists regarding the link between night work and breast cancer, particularly in Korea where 10-15% of workers engage in night shifts.
- Breast cancer is a prevalent cancer among women.
Purpose of the Study:
- To review existing epidemiologic evidence on the relationship between night work and breast cancer.
Main Methods:
- Review of 21 original articles and 5 meta-analyses examining the night work-breast cancer association.
- Investigation into compensation criteria in Denmark related to night work.
Main Results:
- Numerous epidemiologic studies, including cohort, case-control, and meta-analyses, report an association between breast cancer and night work.
- A clear dose-response relationship has not been established for workers with less than 20 years of night work exposure.
Conclusions:
- Despite limitations in current epidemiologic studies, further investigation into breast cancer cases among highly exposed night work individuals is warranted.
- This research is crucial for assessing breast cancer as a potential work-related disease.
Related Concept Videos
02:12Relationship Formation
46.3K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
46.3K
01:18Nightmares and Night Terrors
594
Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares...
Nightmares...
594
01:28Ending Relationships
205
The dissolution of intimate relationships presents complex emotional and psychological challenges, particularly when emotional bonds are strong, the relationship is long-standing, and perceived alternatives are limited. This distress often intensifies in romantic breakups, where the initiator may experience greater turmoil than the rejected partner. Contributing factors include residual attachment, guilt over causing pain, and uncertainty about how to manage the situation. The stress is further...
205
01:27Restless Leg Syndrome and Night Terrors
593
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
593
01:14Pharmacokinetic–Pharmacodynamic Relationship: Duration of Dose-Effect Relationship
23
For drugs producing a quantal response, onset occurs when plasma concentration reaches a minimum effective level (Cmin). The drug's action duration depends on how long the plasma concentration remains above Cmin.Two primary factors influence this duration: dose size and the rate of drug removal from the action site. Both depend on the drug's redistribution to poorly perfused tissues and elimination processes. A larger dose promotes rapid onset and prolongs the effect's duration.Consider a...
23
01:27Relationship Growth
231
Interpersonal relationships progress through stages, beginning with awareness and moving toward mutuality, where emotional connections deepen. While many relationships remain at moderate levels of mutuality, deeper connections form through self-disclosure, trust, and interdependence.Self-DisclosureSelf-disclosure involves revealing personal information, starting with surface-level details and gradually progressing to more intimate content. As trust grows, individuals feel more comfortable...
231