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Updated: Feb 14, 2026
![Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F62460.jpg&w=3840&q=50)
Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging
Published on: July 1, 2021
Value of 18F-FET PET in adult brainstem glioma
Abdulrahman Abdullah Albatly1, Adnan Taleb Alsamarah2, Abdulrahman Alhawas3
1Department of Nuclear Medicine, University Hospital Zurich/University of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland; Department of Diagnostic Radiology, Prince Sultan Medical Military City, Makkah Road, Riyadh, Saudi Arabia.
Purpose:
To investigate 18F-fluoro-ethyl-tyrosine positron emission tomography (FET-PET) imaging characteristics of adult brainstem glioma (BSG).
Materials And Methods:
FET-PET imaging and progression-free survival (PFS) of 16 adult patients with BSG was analyzed (9 high-grade gliomas, 7 low-grade gliomas). SUVmax, TBR, and time activity curves of FET-PET were calculated.
Results:
Progressive gliomas had higher SUVmax (3.57 ± 1.47 vs. 1.60 ± 0.51; p = 0.003) and TBRmax (3.00 ± 1.12 vs. 1.36 ± 0.33; p = 0.001) than stable gliomas. Kaplan-Meier analysis showed longer PFS of tumors with TBRmax < 2.0 compared to tumors with TBRmax > 2.0 (665 ± 32 days versus 220 ± 39 days; p < 0.001).
Conclusion:
FET-PET uptake might be associated with disease progression in adult BSG.
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